Download Bioterrorism - A Medical Dictionary, Bibliography, and by Health Publica Icon Health Publications PDF

By Health Publica Icon Health Publications

This can be a 3-in-1 reference ebook. It offers an entire scientific dictionary overlaying 1000's of phrases and expressions with regards to bioterrorism. It additionally supplies wide lists of bibliographic citations. ultimately, it presents info to clients on the way to replace their wisdom utilizing a variety of web assets. The publication is designed for physicians, clinical scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to familiarize yourself with study devoted to bioterrorism. in case your time is effective, this booklet is for you. First, you won't waste time looking out the net whereas lacking loads of correct info. moment, the publication additionally saves you time indexing and defining entries. ultimately, you won't waste money and time printing enormous quantities of web content.

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Extra resources for Bioterrorism - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

Example text

Objective 2 will identify and characterize inhibitors that block the Zn++-metalloprotease activity of LF, and we will use these data in 3D-Quantitative structure activity relationship (QSAR) computations to optimize the enzyme inhibitors. Objective 3 will test the effectiveness of the EF and LF inhibitors in protecting cultured cells and mice challenged with toxins or B. anthracis. Objective 4 will evaluate the pharmacologic and toxicologic properties of these toxin inhibitors in experimental animals and establish their relative safety.

The program has a faculty of 19, drawn from the Genetics, Immunology and Molecular Microbiology Graduate Programs of the Sackler School of Graduate Biomedical Sciences of Tufts University School of Medicine and New England Medical Center Hospitals. Focused training in the pathogenesis and genetics of microorganisms that are relevant to biodefense will be integrated with training in understanding host responses to these microorganisms. In this way, our 38 Bioterrorism trainees will be prepared to attack biodefense-related problems with an in-depth understanding of pathogen-host interaction.

Currently, there is no vaccine or effective treatment available for Ebola virus infection. While multiple factors contribute to the pathogenesis of Ebola virus infection, the ability of Ebola virus VP35 to abate the host interferon response is critical in determining the outcome of viral infection. VP35 is an essential component required for the Ebola virus RNA replication and nucleocapsid assembly. In addition, VP35 is implicated as an interferon antagonist. When expressed in mammalian cells, VP35 blocked interferon-beta expression and induction of interferon-stimulated response genes triggered by RNA or virus infection.

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